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← ScienceWhich outcome occurs when inhibiting hexokinase within erythrocytes?
A)Decreased glycolysis, ATP production declines✓
B)Increased pentose phosphate pathway flux
C)Elevated NADPH levels, reduced oxidative stress
D)Enhanced osmotic stability, preventing hemolysis
💡 Explanation
Inhibiting hexokinase reduces glucose-6-phosphate production; therefore, decreased glycolysis arises because the initial irreversible commitment step is blocked. This directly limits the entire pathway and thus ATP production declines rather than flux adjusting through alternatives.
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