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Which outcome reduces readout accuracy in DNA microarrays?

A)Constructive interference from probe reflections
B)Quantum tunneling across insulator gaps
C)Brownian motion of tagged molecules
D)Photobleaching after prolonged excitation

💡 Explanation

In DNA microarrays, strong reflections off the substrate can cause constructive interference, which distorts signal intensity and reduces accuracy, because neighboring probes then create overlapping patterns. Therefore constructive interference reduces distinct signal resolution, rather than photobleaching affecting signal degradation.

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