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← ScienceWhich outcome regarding drug efficacy arises when hydrogen bonds stabilize specific protein conformation?
A)Enhanced receptor binding affinity✓
B)Decreased metabolic degradation rate
C)Reduced non-target tissue distribution
D)Increased bioavailability after oral administration
💡 Explanation
Hydrogen bonds maintain the shape; influencing activity pathways because they stabilize the protein's three-dimensional structure to optimize the fit the active site; this interaction supports higher binding affinity rather than changing metabolism, location, or bioavailability of the drug.
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