Which physiological effect occurs in a freshwater fish when the distal tubule in its kidney malfunctions?

💡 Explanation

When the distal tubule malfunctions, sodium reabsorption decreases because the epithelial cells in this part of the nephron cannot properly transport sodium ions from the filtrate back into the bloodstream, leading to ion depletion. Therefore, rapid sodium depletion results, rather than water retention, protein excretion, or cell production, which involve different osmoregulatory mechanisms.

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