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← Human Body & HealthWhich process compromises an immune cell in rheumatoid arthritis?
A)Complement-mediated cell lysis✓
B)Thymic negative selection failure
C)Defective MHC molecule presentation
D)Regulatory T cell dysfunction
💡 Explanation
In rheumatoid arthritis, immune complexes activate the complement system, and the resulting cascade causes complement-mediated cell lysis of cells in the joints, because the generated membrane attack complex causes cell rupture. Therefore, cell lysis intensifies inflammation, rather than limiting expansion by T-cell regulation.
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