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Nature & Animals

Which process inhibits skeletal muscle atrophy during prolonged hibernation in arctic ground squirrels?

A)Enhanced mitochondrial fusion dynamics
B)Increased protein synthesis rates
C)Reduced branched-chain ketoacid dehydrogenase
D)Elevated proteasome degradation activity

💡 Explanation

When squirrels hibernate, they minimize energy expenditure via metabolic suppression; branched-chain ketoacid dehydrogenase activity decreases because it regulates branched-chain amino acid catabolism used for energy, limiting muscle protein breakdown. Therefore reduced BCKDH activity results, rather than enhanced mitochondrial fusion, increased synthesis, or elevated degradation which are inhibited by lower energy demands.

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