Which process is responsible for Gram-positive bacteria's susceptibility to penicillin?

💡 Explanation

Penicillin targets peptidoglycan synthesis, specifically inhibiting transpeptidases that crosslink peptidoglycan chains. Gram-positive bacteria rely heavily on peptidoglycan for cell wall structure, because their cell wall lacks an outer membrane, therefore penicillin is effective against them, rather than bacteria with alternative cell wall compositions or resistance mechanisms.

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