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← ScienceWhich process modifies orbital hybridization during enzymatic catalysis?
A)Local electric field changes✓
B)Vibrational mode quantum tunneling
C)Solvent thermal diffusion changes
D)Substrate-mediated pi-stacking distortion
💡 Explanation
Orbital hybridization changes because shifting electron density alters electrostatic interactions via **electric field induction**. Therefore, orbital shapes mold to accommodate the transition state, rather than resulting purely from vibrational modes or solvent effects.
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