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← Nature & AnimalsWhich signaling cascade disruption prevents full wing formation when juvenile insect molts to pupal stage?
A)Apoptosis inhibition during disc eversion
B)Ecdysone receptor downregulation in cells✓
C)Hedgehog pathway activation errors
D)Toll-NFkB feedback loop interruption
💡 Explanation
During insect metamorphosis, ecdysone triggers molting; receptor downregulation reduces the hormonal signal initiating cell differentiation within imaginal discs, preventing wing development. Therefore receptor downregulation results in wing formation failure, rather than alternative disruptions affecting apoptosis, hedgehog signaling, or immune response feedback.
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