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Human Body & Health

Why does a pituitary adenoma causing excess ACTH secretion lead to increased susceptibility to infections?

A)Elevated TSH suppresses immune cells
B)Hypercortisolism impairs immune function
C)Increased ADH dilutes immune factors
D)Excess GH inhibits lymphocyte production

💡 Explanation

Excess ACTH stimulates the adrenal glands to produce cortisol, and because prolonged hypercortisolism suppresses the function of immune cells, such as lymphocytes and macrophages, this weakens the body's ability to fight off infections. Therefore, option B is correct, rather than TSH, ADH, or GH directly impairing immunity.

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