Why does chronic exposure to organophosphate insecticides cause prolonged muscle paralysis after initial tremors?

💡 Explanation

Organophosphates inhibit acetylcholinesterase, prolonging acetylcholine action in the synaptic cleft; because the action potential duration increases, continuous stimulation causes depolarization block and paralysis. Therefore, inhibition is the correct answer, rather than increased enzymatic activity or neurotransmitter depletion.

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