Why does eccrine sweat gland activity decrease abruptly during rapid ascent to high altitude when air temperature remains constant?

💡 Explanation

During rapid ascent, hypoxia triggers complex stress responses, including alterations in hypothalamic regulation. The hypothalamic set-point for body temperature can shift downwards to conserve energy under conditions of severe stress; because of this set-point shift, thermoregulatory sweating is reduced, rather than increased ADH or adrenal fatigue directly inhibiting sweat glands.

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