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Human Body & Health

Why does elevated inhibin B during ovarian stimulation protocols sometimes prevent successful oocyte retrieval?

A)It blocks LH surge prematurely
B)It causes hyperstimulation syndrome immediately
C)It suppresses FSH secretion selectively
D)It promotes early luteinization directly

💡 Explanation

Elevated inhibin B selectively inhibits FSH secretion through negative feedback because inhibin B is produced by granulosa cells, suppressing further follicle development. Therefore, oocyte retrieval is compromised due to follicle maturation arrest, rather than LH surge blockage or direct luteinization.

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