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Human Body & Health

Why does elevated luteinizing hormone (LH) inhibit follicle-stimulating hormone (FSH) secretion during the luteal phase of the menstrual cycle?

A)Increased estrogen directly stimulates FSH.
B)Inhibin inhibits LH, increasing FSH.
C)High progesterone causes negative feedback.
D)Prolactin inhibits GnRH, raising FSH.

💡 Explanation

High progesterone levels during the luteal phase cause negative feedback on the hypothalamus and pituitary gland, thus reducing GnRH and FSH secretion, because the corpus luteum needs to maintain itself and prepare the uterine lining for implantation; therefore, this progesterone effect occurs, rather than stimulation by estrogen or inhibin modulation.

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