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← Human Body & HealthWhy does persistent hyperthyroidism increase the risk of osteoporosis in older adults?
A)Increased calcitonin inhibits osteoblasts
B)Elevated TSH directly stimulates osteoclasts
C)Reduced cortisol downregulates bone formation
D)Excess thyroid hormone accelerates bone turnover✓
💡 Explanation
Hyperthyroidism causes excessive thyroid hormone (T3 and T4) secretion, which accelerates the rate of bone remodeling. This means that bone resorption by osteoclasts exceeds bone formation by osteoblasts, because thyroid hormones stimulate osteoclast activity. Therefore, bone density decreases, rather than increasing through stimulated osteoblast activity, increasing the risk of osteoporosis.
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