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← Human Body & HealthWhy does plasma osmolality sharply increase in a patient undergoing dialysis when the dialysate's sodium concentration is transiently set too high?
A)Sodium excretion increases, decreasing water retention
B)Renin secretion is suppressed, reducing sodium retention
C)Intracellular fluid shifts cause hyponatremic encephalopathy
D)Osmoreceptors trigger ADH release, increasing water reabsorption✓
💡 Explanation
Increased dialysate sodium causes a rapid rise in plasma sodium during dialysis, which triggers the osmoreceptor-ADH mechanism to conserve water at the kidneys. This happens because the body attempts to dilute the elevated plasma osmolality; therefore, ADH release increases water reabsorption rather than sodium excretion.
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