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Human Body & Health

Why does prolonged use of topical corticosteroids increase the risk of skin infections more than barrier creams?

A)Reduced keratinocyte turnover occurs
B)Immune cell activity is suppressed
C)Increased sebum production results
D)Collagen synthesis rates accelerate

💡 Explanation

Topical corticosteroids suppress local immune cell activity, impairing the skin's ability to fight off infections, because they reduce inflammation and immune response. Therefore, infections are more likely; barrier creams support physical barrier function rather than directly affecting immune cell activity.

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