Why does the skin of individuals with overactive sebaceous glands and impaired skin barrier function develop acne lesions more readily than those with normal sebum production?

💡 Explanation

Increased sebum provides nutrients for Cutibacterium acnes, leading to bacterial proliferation and inflammation within hair follicles. Because the skin barrier is impaired, inflammatory mediators cannot be contained, therefore acne lesions develop more readily, rather than normal desquamation occurring.

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