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Human Body & Health

A patient with a known peanut allergy experiences sudden respiratory distress after accidentally ingesting peanut oil. Which mechanism explains this acute allergic reaction?

A)Increased regulatory T cell activity
B)Mast cell degranulation via IgE
C)Complement cascade activation via IgG
D)Enhanced macrophage phagocytosis of allergen

💡 Explanation

Mast cell degranulation causes the acute allergic reaction because the peanut allergen cross-links IgE antibodies on mast cells, triggering the release of histamine and other inflammatory mediators. Therefore, option B is correct, rather than the other options which do not represent the immediate hypersensitivity response.

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