A patient with liver cirrhosis experiences prolonged bleeding after a minor injury. Which mechanism explains why reduced fibrin crosslinking leads to this bleeding tendency?

💡 Explanation

Liver cirrhosis impairs the liver's ability to produce clotting factors, including those responsible for fibrin crosslinking. Because fibrin crosslinking stabilizes blood clots, reduced crosslinking weakens the clot structure, therefore increasing fibrinolysis and leading to prolonged bleeding, rather than directly affecting thrombin activation or platelet adhesion.

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