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Human Body & Health

A patient with pulmonary fibrosis experiences reduced gas exchange. Why does the blood's oxygen saturation drop despite increased ventilation rate?

A)Lowered hemoglobin-oxygen binding affinity
B)Increased alveolar membrane diffusion distance
C)Reduced pulmonary capillary blood volume
D)Elevated metabolic rate of lung cells

💡 Explanation

The blood's oxygen saturation drops because pulmonary fibrosis thickens the alveolar membrane, increasing the diffusion distance for oxygen. Therefore, even with increased ventilation, oxygen diffusion is impaired, rather than the oxygen being able to efficiently cross into the bloodstream.

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