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← Human Body & HealthWhy does a deep skin laceration in an elderly individual often exhibit impaired healing compared to a similar injury in a younger person?
A)Reduced inflammatory cytokine production predominates
B)Increased neutrophil chemotaxis becomes accelerated
C)Diminished collagen synthesis impairs matrix remodeling✓
D)Accelerated fibroblast apoptosis promotes scar formation
💡 Explanation
Impaired healing occurs due to reduced collagen production in the elderly. Collagen synthesis by fibroblasts is essential for extracellular matrix remodeling and wound closure because aging diminishes fibroblast activity and collagen production; therefore, the wound repair is less efficient, rather than faster neutrophil chemotaxis or accelerated apoptosis promoting scar formation.
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