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Human Body & Health

A researcher introduces a novel antigen into a mouse model lacking mature B lymphocytes. Which consequence follows regarding adaptive immune response?

A)Rapid IgG antibody production occurs
B)T-cell dependent antibody production impaired
C)Normal IgE-mediated mast cell degranulation
D)Efficient direct cytotoxic T lymphocyte activity

💡 Explanation

T-cell dependent antibody production is impaired because B lymphocytes are required to present antigen to T helper cells, thereby activating them. Therefore, without functional B cells, T cell-mediated antibody production is hindered, rather than alternative scenarios that depend less on B cell interaction.

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