An individual exhibits impaired collagen synthesis during wound healing, leading to weakened scar tissue. Which mechanism explains this phenomenon in the context of Vitamin C deficiency?

💡 Explanation

Vitamin C acts as a cofactor for prolyl hydroxylase and lysyl hydroxylase, enzymes crucial for collagen stabilization. Because Vitamin C deficiency reduces prolyl hydroxylase activity, collagen synthesis is impaired, therefore weakened scar tissue forms, rather than proper collagen crosslinking.

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