An individual taking an SSRI antidepressant experiences increased serotonin levels in the synaptic cleft. Which effect dominates in the postsynaptic neuron due to this change?

💡 Explanation

SSRI antidepressants increase serotonin levels in the synaptic cleft by blocking its reuptake. Because the serotonin remains available for a longer duration, it prolongs activation of postsynaptic receptors, therefore the correct answer is prolonged receptor activation, rather than decreased action potential frequency from reduced stimulation.

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