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Human Body & Health

An individual with advanced liver disease experiences impaired synthesis of several coagulation factors. Which outcome is most directly attributable to this impairment, leading to increased risk of hemorrhage?

A)Elevated red blood cell production
B)Increased platelet aggregation rate
C)Decreased thrombin formation efficiency
D)Accelerated fibrinolysis cascade activation

💡 Explanation

Impaired synthesis of coagulation factors in liver disease directly reduces thrombin formation efficiency, because these factors are essential for the clotting cascade. Therefore, reduced thrombin results in inadequate fibrin production to stabilize clots, rather than other effects like accelerated clot breakdown.

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