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Human Body & Health

During a bone marrow transplant, if the recipient's immune system recognizes ABO blood group antigens on the donor's red blood cells as foreign, which consequence follows?

A)Erythropoiesis receives a boost stimulus
B)Clonal deletion of B lymphocytes ensues
C)Hematopoietic stem cells differentiate effectively
D)Acute hemolytic transfusion reaction occurs

💡 Explanation

An acute hemolytic transfusion reaction occurs because pre-existing antibodies in the recipient's plasma bind to the donor's red blood cell antigens, activating the complement system and causing intravascular hemolysis; therefore, a hemolytic reaction occurs, rather than erythropoiesis stimulation, B lymphocyte deletion, or effective stem cell differentiation.

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