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Human Body & Health

If a bee sting introduces venom into a person, and they develop systemic vasodilation, bronchoconstriction, and increased vascular permeability, which process explains this reaction?

A)Complement system anaphylatoxin production
B)Direct venom-induced mast cell lysis
C)IgE-mediated mast cell degranulation
D)T-cell mediated cytotoxicity cascade

💡 Explanation

Bee sting venom can trigger an allergic reaction through IgE-mediated mast cell degranulation. The IgE antibodies, pre-sensitized to venom antigens, bind to mast cells, and upon encountering the allergen, cause the release of histamine and other mediators that lead to vasodilation, bronchoconstriction and increased vascular permeability; therefore, C is correct, rather than direct lysis or T-cell activation, because this specific reaction is a classic type I hypersensitivity.

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