If a drug increases the sensitivity of hypothalamic neurons to leptin, which consequence follows regarding energy homeostasis?

💡 Explanation

Leptin signals satiety to the hypothalamus, therefore increased sensitivity enhances this effect, leading to reduced appetite and food intake due to enhanced activation of satiety pathways. This response regulates energy balance, rather than affecting ghrelin, metabolic rate, or glycogen synthesis directly, because leptin primarily influences appetite.

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