If a genetically predisposed individual with elevated IgE antibodies consumes peanuts, which consequence directly results from mast cell degranulation in their small intestine?

💡 Explanation

Mast cell degranulation releases histamine and other mediators that disrupt tight junctions between intestinal epithelial cells, increasing permeability, because this allows allergens to enter the bloodstream. Therefore, increased permeability is the correct consequence, rather than immune tolerance or localized mucus production.

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