If a growth factor receptor mutation allows a cancer cell to bypass the G1/S checkpoint while also impairing the intrinsic mitochondrial apoptosis pathway, which consequence follows?

💡 Explanation

Chemotherapy often induces apoptosis; therefore, if the intrinsic apoptotic pathway is impaired due to the receptor mutation, the cell becomes resistant. This is because the drug cannot trigger cell death effectively, rather than enhanced repair or immune detection.

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