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Human Body & Health

If a hospital patient's urinary tract infection, initially susceptible to a specific antibiotic, develops resistance after several days, which mechanism most likely explains the rapid adaptation?

A)Increased antibiotic degradation in bladder
B)Mutation in bacterial ribosomal binding site
C)Horizontal gene transfer via plasmids
D)Downregulation of porin channel expression

💡 Explanation

Horizontal gene transfer involving plasmids allows for the quick spread of antibiotic resistance genes between bacteria because these plasmids can carry genes encoding resistance and transfer them rapidly; therefore, resistance emerges quickly, rather than only through slower mutational processes or localized changes in degradation.

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