If a neurotoxin selectively blocks Piezo2 channels in human Pacinian corpuscles, which sensory effect follows?

💡 Explanation

Pacinian corpuscles are responsible for sensing vibration via the activation of Piezo2 channels. Therefore, if these channels are blocked by a neurotoxin, the mechanotransduction mechanism is disrupted, and the individual loses the ability to detect vibrations, rather than pressure or temperature, because those are sensed by different receptors.

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