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← Human Body & HealthIf a novel influenza virus infects a previously unexposed individual, which mechanism explains why antibody production initially remains low, despite the activation of the innate immune system?
A)B-cell tolerance checkpoints halt activation
B)Germinal center formation requires time✓
C)T-helper cells exhibit immediate exhaustion
D)Complement cascade directly inhibits antibodysecretion
💡 Explanation
Antibody production is initially low because the adaptive immune response, specifically germinal center formation, takes several days to develop. Therefore, isotype switching and affinity maturation processes are delayed, rather than immediate B-cell activation or complement inhibition, which play different roles.
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