If a patient chronically underproduces incretin hormones like GLP-1 after meals, which consequence related to blood glucose regulation is most likely to dominate?

💡 Explanation

Reduced GLP-1 leads to decreased insulin secretion because GLP-1 normally amplifies insulin release from pancreatic beta cells after a meal. Therefore, reduced postprandial insulin secretion is the dominant effect, rather than increased glycogen synthesis or enhanced insulin sensitivity, which are normally stimulated by insulin.

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