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Human Body & Health

If a patient exhibits alkalosis during surgery, which consequence related to blood oxygen transport is most likely?

A)Increased hemoglobin-oxygen affinity, higher unloading
B)Decreased 2,3-BPG binding, right shift
C)Enhanced carbon dioxide unloading, Haldane effect
D)Increased hemoglobin-oxygen affinity, lower unloading

💡 Explanation

Alkalosis increases blood pH, which enhances hemoglobin's affinity for oxygen, causing less oxygen to be released to tissues. This occurs because the Bohr effect dictates that higher pH reduces proton concentration, stabilizing the R state of hemoglobin; therefore, oxygen unloading decreases, rather than increases as in acidosis.

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