If a patient experiences persistent inflammation after an initial immune response, which consequence is most likely to impair the resolution phase?

💡 Explanation

The resolution phase requires the removal of dead cells via efferocytosis; if apoptotic neutrophils aren't cleared, inflammation persists because they can release pro-inflammatory mediators. Therefore, dysfunctional efferocytosis impairs resolution, rather than normal COX activity, increased vagal stimulation, or elevated omega-3 levels, which typically promote resolution.

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