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← Human Body & HealthIf a patient reports chronic pain following a nerve injury where A-beta fibers now activate pain pathways in the spinal cord, which consequence follows?
A)Increased endorphin receptor sensitivity
B)Allodynia via central sensitization✓
C)Reduced substance P neurotransmission
D)Elevated descending inhibitory signaling
💡 Explanation
Allodynia, pain from non-painful stimuli, can result from central sensitization because nerve damage can cause A-beta fibers to trigger nociceptor pathways. This altered transmission leads to pain perception, therefore the correct answer is allodynia rather than endorphin release, substance P reduction, or increased inhibition which would reduce pain.
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