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Human Body & Health

If a patient's iodine intake suddenly increases fivefold while they are taking a constant dose of thyroid hormone replacement, which consequence follows in the thyroid hormone production pathway?

A)Increased TSH receptor sensitivity
B)Decreased T4 to T3 conversion
C)Upregulation of thyroid peroxidase
D)Transient suppression of thyroid hormone

💡 Explanation

The Wolff-Chaikoff effect causes transient suppression of thyroid hormone production when iodine intake acutely increases because excess iodide inhibits thyroid peroxidase, reducing thyroid hormone synthesis; therefore, thyroid hormone levels will be transiently suppressed, rather than increasing TSH sensitivity or T4 conversion.

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