If a patient with a thyroid hormone synthesis deficiency begins taking an amiodarone medication, which consequence follows?

💡 Explanation

Amiodarone inhibits the enzyme deiodinase, which converts T4 to the more active T3. Because amiodarone further reduces the available T3 in a patient already deficient in thyroid hormone synthesis, therefore decreased T4 to T3 conversion occurs, rather than increased TSH sensitivity or thyroglobulin production.

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