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Human Body & Health

If a patient with a thyroid tumor begins overproducing T4, which consequence affecting peripheral tissue is most likely?

A)Decreased cellular ATP production
B)Increased expression of TRα1 receptors
C)Reduced heart rate variability
D)Enhanced glycogen synthesis in hepatocytes

💡 Explanation

Increased thyroid hormone levels from the tumor will cause upregulation of thyroid hormone receptors (TRα1) in peripheral tissues because of genomic regulation; therefore, receptor expression increases, rather than decreased ATP production or altered glycogen metabolism, which are longer-term adaptations, not direct gene expression changes.

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