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Human Body & Health

If a pharmaceutical company develops a drug that inhibits the dimerization of intracellular steroid hormone receptors after ligand binding, which consequence follows?

A)Increased hormone production by glands
B)Enhanced cellular response to the hormone
C)Decreased hormone transport in bloodstream
D)Impaired receptor translocation to nucleus

💡 Explanation

Steroid hormone receptor dimerization is essential for translocation to the nucleus and subsequent gene transcription; because dimerization is blocked, nuclear entry is impaired. Therefore, the intracellular signaling cascade is disrupted, rather than increased hormone production, enhanced response, or affecting hormone transport.

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