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Human Body & Health

If a researcher introduces a telomerase inhibitor to cells undergoing division in vitro, which consequence follows for chromosome stability?

A)Increased rate of genetic mutations
B)Higher levels of homologous recombination
C)Enhanced protection against oxidative damage
D)Progressive telomere shortening, instability

💡 Explanation

Telomerase is responsible for maintaining telomere length. Introducing a telomerase inhibitor will cause progressive telomere shortening during cell division, because the cell lacks the enzyme to replenish the telomere sequence; therefore, chromosomal instability increases, rather than the other protective or mutative outcomes.

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