If a tumor compresses lymphatic vessels in the groin, which consequence follows regarding fluid dynamics in the lower extremities?

💡 Explanation

Lymphatic compression impairs fluid drainage from the interstitial space, leading to protein accumulation there because proteins cannot easily re-enter blood capillaries. Therefore, the interstitial fluid osmotic pressure increases, rather than a change in venous return or capillary dynamics which are more directly affected by the cardiovascular system.

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