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← Human Body & HealthIf cyclical mechanical stress on a long bone is reduced due to prolonged bed rest, which consequence follows regarding bone remodeling?
A)Osteoblast differentiation becomes upregulated
B)Osteoclast activity exceeds osteoblast activity✓
C)Hydroxyapatite crystal deposition increases
D)Bone mineral density remains constant
💡 Explanation
Reduced mechanical stress inhibits osteoblast activity while osteoclast activity continues, leading to bone resorption, because bone adapts to stress; therefore, bone mineral density decreases, rather than remaining constant as osteoclast activity increases, resulting in weaker bones.
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