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Human Body & Health

In a patient undergoing chemotherapy, why does aplastic anemia frequently manifest as thrombocytopenia and neutropenia in addition to erythrocyte deficiency?

A)Increased erythropoietin selectively depletes other cells
B)Bone marrow stem cells are globally suppressed
C)Immune cross-reactivity targets various blood cells
D)Splenic sequestration accelerates cell removal

💡 Explanation

Aplastic anemia, particularly in chemotherapy patients, often presents as pancytopenia because chemotherapeutic agents damage bone marrow stem cells, which are responsible for producing all blood cell lineages. Therefore, erythrocytes, thrombocytes, and neutrophils are all reduced rather than a single cell type, because of stem cell suppression.

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