In a patient with compromised kidney function, which outcome results when glomerular filtration rate (GFR) decreases significantly due to inflammation and reduced capillary permeability?

💡 Explanation

Reduced GFR leads to less effective filtration in the nephrons because the compromised capillaries filter less fluid and fewer waste products. Therefore, urea and other toxins accumulate in the bloodstream, rather than being excreted, and the other options do not directly result from reduced filtration.

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