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Human Body & Health

What causes bowing of leg bones in children affected by rickets?

A)Osteoclast hyperactivity degrades bone
B)Insufficient calcium phosphate mineralization
C)Increased collagen fiber deposition
D)Elevated parathyroid hormone reabsorption

💡 Explanation

Rickets causes bone deformities, such as bowed legs, because vitamin D deficiency leads to impaired calcium absorption. This results in insufficient calcium phosphate mineralization of the bone matrix, therefore bone softens under weight-bearing stress, rather than maintaining its rigid structure due to normal mineralization processes.

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