What distinguishes the urea cycle in the liver from the Cori cycle during prolonged starvation?

💡 Explanation

The Cori cycle converts lactate produced by anaerobic glycolysis in muscles back to glucose in the liver via gluconeogenesis; this differs from the urea cycle, which detoxifies ammonia. Therefore, the Cori cycle's primary function is lactate recycling, rather than direct detoxification or ATP provision, because it is focused on glucose homeostasis.

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