What happens to long-term potentiation (LTP) in hippocampal neurons when protein synthesis inhibitors are applied after tetanic stimulation?

💡 Explanation

Protein synthesis is required for the consolidation of late-phase LTP because it involves the production of new proteins essential for structural changes at the synapse. Therefore, inhibiting protein synthesis impairs the maintenance of late-phase LTP, rather than early-phase LTP which does not rely on new protein production.

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